Regina George is the meanest of all the girls in Mean Girls and these memorable quotes prove that she truly is evil in human form.

For a character who doesn’t kill anyone or physically attack anyone, Regina George from Mean Girls is considerably evil. As far as high-school girls go, she might be one of the most malevolent of her kind. Janis Ian even explains to Cady that “evil takes a human form” in Regina, and when viewers let some of her nastiest lines sink in, it’s easy to see why.

The comments that Regina makes clearly show that she cares about nobody but herself, does not feel guilty about being two-faced and judgemental and has no problem ordering people around like they’re slaves.

Updated on January 28th, 2021 by Scoot Allan: 2004's Mean Girls introduced fans to a group of young girls known around the school as the 'Plastics" who were led by Rachel McAdam's Regina George, the meanest of the mean who was labeled as pure evil. Mean Girls has continued to draw in new audiences over the years both with the movie, a musical adaptation, and a book that has furthered Regina's evil legend, so we are taking another look at some of the worst things said by Regina that prove she really is the evilest high school girl.

15 "Then It's Settled, So You Can Go Shave Your Back Now."

While Regina's statements to Jason early in the movie are in defense of her friend Gretchen, as he was scheming with Cady right in front of them after going with Gretchen to an earlier party at Regina's, but it's still pretty mean to say in a cafeteria full of students.

She first put Cady on the spot by asking her if she wanted to have sex with Jason, and when she said no, she further humiliated Jason. He was being very inappropriate so it may have been deserved, but it was a good indicator of Regina's ability to publicly take down her classmates.

14 "So You Agree, You Think You're Really Pretty."

Regina used a particular brand of double-talk and fake compliments to both hide insults and manipulate her closest friends into turning on each other, which she did a number of times throughout Mean Girls to break down her friends and maintain control of the Plastics.

After complementing Cady on her prettiness during their first meeting, she turned it on her potential new friend almost immediately after she agreed, making her feel guilty about the compliment and highlighting Regina's manipulative behavior.